| pubmed-article:10477551 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0525013 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0524892 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0086222 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C1551336 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0013879 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:10477551 | lifeskim:mentions | umls-concept:C1705733 | lld:lifeskim |
| pubmed-article:10477551 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:10477551 | pubmed:dateCreated | 1999-10-14 | lld:pubmed |
| pubmed-article:10477551 | pubmed:abstractText | Transgenic expression constructs were employed to identify a cis-acting transcription element in the T cell receptor (TCR)-gamma locus, called HsA, between the Vgamma5 and Vgamma2 genes. In constructs lacking the previously defined enhancer (3'E(Cgamma1)), HsA supports transcription in mature but not immature T cells in a largely position-independent fashion. 3'E(Cgamma1), without HsA, supports transcription in immature and mature T cells but is subject to severe position effects. Together, the two elements support expression in immature and mature T cells in a copy number-dependent, position-independent fashion. Furthermore, HsA was necessary for consistent rearrangement of transgenic recombination substrates. These data suggest that HsA provides chromatin-opening activity and, together with 3'E(Cgamma1), constitutes a T cell-specific locus control region for the TCR-gamma locus. | lld:pubmed |
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| pubmed-article:10477551 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10477551 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10477551 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10477551 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10477551 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10477551 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:10477551 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:10477551 | pubmed:author | pubmed-author:ChenTT | lld:pubmed |
| pubmed-article:10477551 | pubmed:author | pubmed-author:CadiNN | lld:pubmed |
| pubmed-article:10477551 | pubmed:author | pubmed-author:RauletD HDH | lld:pubmed |
| pubmed-article:10477551 | pubmed:author | pubmed-author:BakerJ EJE | lld:pubmed |
| pubmed-article:10477551 | pubmed:author | pubmed-author:KannSS | lld:pubmed |
| pubmed-article:10477551 | pubmed:author | pubmed-author:XiongNN | lld:pubmed |
| pubmed-article:10477551 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10477551 | pubmed:day | 6 | lld:pubmed |
| pubmed-article:10477551 | pubmed:volume | 190 | lld:pubmed |
| pubmed-article:10477551 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10477551 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10477551 | pubmed:pagination | 669-79 | lld:pubmed |
| pubmed-article:10477551 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:10477551 | pubmed:meshHeading | pubmed-meshheading:10477551... | lld:pubmed |
| pubmed-article:10477551 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10477551 | pubmed:articleTitle | A novel element upstream of the Vgamma2 gene in the murine T cell receptor gamma locus cooperates with the 3' enhancer to act as a locus control region. | lld:pubmed |
| pubmed-article:10477551 | pubmed:affiliation | Department of Molecular and Cell Biology and Cancer Research Laboratory, University of California at Berkeley, Berkeley, California 94720, USA. | lld:pubmed |
