| pubmed-article:10450972 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C1554184 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:10450972 | lifeskim:mentions | umls-concept:C0301869 | lld:lifeskim |
| pubmed-article:10450972 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:10450972 | pubmed:dateCreated | 1999-9-24 | lld:pubmed |
| pubmed-article:10450972 | pubmed:abstractText | The synthesis of a novel antithrombotic consisting of a heparin pentasaccharide conjugated to the active site inhibitor N-(2-naphtalenesulfonyl)-glycyl-(D)-4-aminophenyl-alanyl-piperidin e (NAPAP) (i.e. compound I) is reported. This conjugate shows a unique pharmacological profile both in vitro and in vivo having direct anti-thrombin and ATIII-mediated anti-Xa activity. Furthermore, conjugate I has a prolonged in vivo half-life compared to NAPAP (1.5 h vs 9 min.). | lld:pubmed |
| pubmed-article:10450972 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10450972 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10450972 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10450972 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10450972 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10450972 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10450972 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10450972 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10450972 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:10450972 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:10450972 | pubmed:author | pubmed-author:van BoomJ HJH | lld:pubmed |
| pubmed-article:10450972 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:10450972 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:10450972 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:10450972 | pubmed:author | pubmed-author:BastenJ EJE | lld:pubmed |
| pubmed-article:10450972 | pubmed:author | pubmed-author:BuijsmanR CRC | lld:pubmed |
| pubmed-article:10450972 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10450972 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:10450972 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10450972 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10450972 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10450972 | pubmed:pagination | 2013-8 | lld:pubmed |
| pubmed-article:10450972 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:10450972 | pubmed:meshHeading | pubmed-meshheading:10450972... | lld:pubmed |
| pubmed-article:10450972 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10450972 | pubmed:articleTitle | Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action. | lld:pubmed |
| pubmed-article:10450972 | pubmed:affiliation | Leiden Institute of Chemistry, Gorlaeus Laboratories, The Netherlands. | lld:pubmed |
| pubmed-article:10450972 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:10450972 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10450972 | lld:pubmed |
