| pubmed-article:10385624 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10385624 | lifeskim:mentions | umls-concept:C0242606 | lld:lifeskim |
| pubmed-article:10385624 | lifeskim:mentions | umls-concept:C1516509 | lld:lifeskim |
| pubmed-article:10385624 | lifeskim:mentions | umls-concept:C0728940 | lld:lifeskim |
| pubmed-article:10385624 | lifeskim:mentions | umls-concept:C1336767 | lld:lifeskim |
| pubmed-article:10385624 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:10385624 | lifeskim:mentions | umls-concept:C2331150 | lld:lifeskim |
| pubmed-article:10385624 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:10385624 | pubmed:dateCreated | 1999-8-5 | lld:pubmed |
| pubmed-article:10385624 | pubmed:abstractText | Hydrogen peroxide (H2O2), a reactive oxygen species (ROS), is known to induce oxidative stress and apoptosis. U937 cells treated with H2O2 were shown to produce high molecular weight (HMW) DNA fragments approximately 50 to 100 kb in size in <1 min. The formation of these HMW DNA fragments is reversible and shown to be mediated by DNA topoisomerase II (TOP2). Following this initial event, formation of irreversible HMW DNA fragments and nucleosomal ladders occurs. Our results thus demonstrate a potential role of TOP2 in oxidative damage of DNA and apoptotic cell death. | lld:pubmed |
| pubmed-article:10385624 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10385624 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10385624 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10385624 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10385624 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:10385624 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:10385624 | pubmed:author | pubmed-author:LiT KTK | lld:pubmed |
| pubmed-article:10385624 | pubmed:author | pubmed-author:WangHH | lld:pubmed |
| pubmed-article:10385624 | pubmed:author | pubmed-author:LiuL FLF | lld:pubmed |
| pubmed-article:10385624 | pubmed:author | pubmed-author:YoII | lld:pubmed |
| pubmed-article:10385624 | pubmed:author | pubmed-author:MajTT | lld:pubmed |
| pubmed-article:10385624 | pubmed:author | pubmed-author:ChenA YAY | lld:pubmed |
| pubmed-article:10385624 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10385624 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:10385624 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:10385624 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10385624 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10385624 | pubmed:pagination | 1553-60 | lld:pubmed |
| pubmed-article:10385624 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:meshHeading | pubmed-meshheading:10385624... | lld:pubmed |
| pubmed-article:10385624 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10385624 | pubmed:articleTitle | Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress. | lld:pubmed |
| pubmed-article:10385624 | pubmed:affiliation | Department of Pharmacology, University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA. | lld:pubmed |
| pubmed-article:10385624 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10385624 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10385624 | lld:pubmed |
