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pubmed-article:10233367pubmed:abstractTextAn expansion of CD8+ lymphocytes associated with a monoclonal rearrangement of the T-cell receptor gamma locus was found in a woman with HIV-1 infection. A subpopulation of HIV-positive patients display an unusual response to HIV infection characterized by a persistent marked CD8+ lymphocytosis, the presence of which appears to be associated with an improved long-term prognosis. This condition is thought to represent a florid immune response to an ongoing viral infection which may be HIV itself, and suggests that monoclonal proliferation of CD8+ lymphocytes does not imply the presence of an underlying malignant process.lld:pubmed
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pubmed-article:10233367pubmed:articleTitleParaproteins and monoclonal expansion of CD3+CD8+ CD56-CD57+ T lymphocytes in a patient with HIV infection.lld:pubmed
pubmed-article:10233367pubmed:affiliationDepartment of Genitourinary Medicine, Royal Hositals NHS Trust, Whitechapel, London.lld:pubmed
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