Linked Life Data

10066759

Source:http://linkedlifedata.com/resource/pubmed/id/10066759

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:10066759rdf:typepubmed:Citationlld:pubmed
pubmed-article:10066759lifeskim:mentionsumls-concept:C0020792lld:lifeskim
pubmed-article:10066759lifeskim:mentionsumls-concept:C1260937lld:lifeskim
pubmed-article:10066759lifeskim:mentionsumls-concept:C0205131lld:lifeskim
pubmed-article:10066759lifeskim:mentionsumls-concept:C0035547lld:lifeskim
pubmed-article:10066759lifeskim:mentionsumls-concept:C0023688lld:lifeskim
pubmed-article:10066759lifeskim:mentionsumls-concept:C1167622lld:lifeskim
pubmed-article:10066759lifeskim:mentionsumls-concept:C0386041lld:lifeskim
pubmed-article:10066759pubmed:issue11lld:pubmed
pubmed-article:10066759pubmed:dateCreated1999-4-13lld:pubmed
pubmed-article:10066759pubmed:abstractTextThe ribonucleoside triphosphate reductase (RTPR) from Lactobacillus leichmannii catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates and uses coenzyme B12, adenosylcobalamin (AdoCbl), as a cofactor. Use of a mechanism-based inhibitor, 2'-deoxy-2'-methylenecytidine 5'-triphosphate, and isotopically labeled RTPR and AdoCbl in conjunction with EPR spectroscopy has allowed identification of the lower axial ligand of cob(II)alamin when bound to RTPR. In common with the AdoCbl-dependent enzymes catalyzing irreversible heteroatom migrations and in contrast to the enzymes catalyzing reversible carbon skeleton rearrangements, the dimethylbenzimidazole moiety of the cofactor is not displaced by a protein histidine upon binding to RTPR.lld:pubmed
pubmed-article:10066759pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:languageenglld:pubmed
pubmed-article:10066759pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:citationSubsetIMlld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10066759pubmed:statusMEDLINElld:pubmed
pubmed-article:10066759pubmed:monthMarlld:pubmed
pubmed-article:10066759pubmed:issn0021-9258lld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:RéteyJJlld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:LawrenceC CCClld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:NitscheRRlld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:RobinsM JMJlld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:StubbsDDlld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:SamanoVVlld:pubmed
pubmed-article:10066759pubmed:authorpubmed-author:GerfenG JGJlld:pubmed
pubmed-article:10066759pubmed:issnTypePrintlld:pubmed
pubmed-article:10066759pubmed:day12lld:pubmed
pubmed-article:10066759pubmed:volume274lld:pubmed
pubmed-article:10066759pubmed:ownerNLMlld:pubmed
pubmed-article:10066759pubmed:authorsCompleteYlld:pubmed
pubmed-article:10066759pubmed:pagination7039-42lld:pubmed
pubmed-article:10066759pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:meshHeadingpubmed-meshheading:10066759...lld:pubmed
pubmed-article:10066759pubmed:year1999lld:pubmed
pubmed-article:10066759pubmed:articleTitleBinding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligand.lld:pubmed
pubmed-article:10066759pubmed:affiliationDepartments of Chemistry and Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.lld:pubmed
pubmed-article:10066759pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10066759pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:10066759pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10066759lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10066759lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10066759lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10066759lld:pubmed