| pubmed-article:10023966 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10023966 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:10023966 | pubmed:issue | 9146 | lld:pubmed |
| pubmed-article:10023966 | pubmed:dateCreated | 1999-3-4 | lld:pubmed |
| pubmed-article:10023966 | pubmed:abstractText | Leukotriene-receptor antagonists are the first novel class of antiasthma drugs to become available over the past three decades. They have an unique profile in that they are a hybrid of an anti-inflammatory and bronchodilator drug, and they can be taken as a tablet once or twice daily. The published data with leukotriene-receptor antagonists such as montelukast or zafirlukast show good antiasthmatic activity over a wide spectrum of asthma severity either as monotherapy or with inhaled steroids. Another potential spin-off of leukotriene-receptor antagonists is that they also seem to be effective in treating allergic rhinitis, which commonly coexists in patients with asthma. Here I overview the clinical pharmacology of leukotriene antagonists and appraise the published data from clinical trials, and look at the appropriate position of these agents in asthma management guidelines. | lld:pubmed |
| pubmed-article:10023966 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10023966 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10023966 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10023966 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:10023966 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10023966 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10023966 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10023966 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:10023966 | pubmed:issn | 0140-6736 | lld:pubmed |
| pubmed-article:10023966 | pubmed:author | pubmed-author:LipworthB JBJ | lld:pubmed |
| pubmed-article:10023966 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10023966 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:10023966 | pubmed:volume | 353 | lld:pubmed |
| pubmed-article:10023966 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10023966 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10023966 | pubmed:pagination | 57-62 | lld:pubmed |
| pubmed-article:10023966 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:10023966 | pubmed:meshHeading | pubmed-meshheading:10023966... | lld:pubmed |
| pubmed-article:10023966 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10023966 | pubmed:articleTitle | Leukotriene-receptor antagonists. | lld:pubmed |
| pubmed-article:10023966 | pubmed:affiliation | Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital and Medical School, University of Dundee, UK. b.j.lipworth@dundee.uk | lld:pubmed |
| pubmed-article:10023966 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10023966 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10023966 | pubmed:publicationType | Review | lld:pubmed |
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