| pubmed-article:1001973 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0019166 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0008679 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0023884 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0009498 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C0003313 | lld:lifeskim |
| pubmed-article:1001973 | lifeskim:mentions | umls-concept:C1446409 | lld:lifeskim |
| pubmed-article:1001973 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:1001973 | pubmed:dateCreated | 1977-2-26 | lld:pubmed |
| pubmed-article:1001973 | pubmed:abstractText | One hundred and fifty-two biopsies from serologically HBsAg positive and negative patients with liver disease were studied in immunofluorescence: for the presence of the surface (HBs) and the core (HBc) antigenic determinants foeterminants of the hepatitis B virus, of immunoglobulins and complement (C) deposits, and for the capacity to fix human C. Circumstantial evidence is presented suggesting that HBc immune-complexes are a relevant feature in the establishment and progression of chronic HBSAg liver disease. C fixation by liver cells was shown in all HBC positive patients with chronic hepatitis; an active form was present in every case, except two with a persistent hepatitis, an inverse ratio of HBc to C binding fluorescence being noted between active chronic hepatitis and cirrhotic patients. HBc without C fixation was observed in only three patients in the incubation phase of infectious hepatitis. IgG deposits were often found in HBc containing, C fixing nuclei. No C binding or IgG deposits were observed in acute self-limited type B hepatitis, in serologically positive patients with normal liver or minimal histological lesions, with and without HBs cytoplasmic fluorescence in their biopsy, or in serologically negative individuals. | lld:pubmed |
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| pubmed-article:1001973 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1001973 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1001973 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1001973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1001973 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1001973 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1001973 | pubmed:issn | 0017-5749 | lld:pubmed |
| pubmed-article:1001973 | pubmed:author | pubmed-author:VermaKK | lld:pubmed |
| pubmed-article:1001973 | pubmed:author | pubmed-author:RizzettoMM | lld:pubmed |
| pubmed-article:1001973 | pubmed:author | pubmed-author:CrivelliOO | lld:pubmed |
| pubmed-article:1001973 | pubmed:author | pubmed-author:CaneseM GMG | lld:pubmed |
| pubmed-article:1001973 | pubmed:author | pubmed-author:BoninoFF | lld:pubmed |
| pubmed-article:1001973 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1001973 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:1001973 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1001973 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1001973 | pubmed:pagination | 837-43 | lld:pubmed |
| pubmed-article:1001973 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:1001973 | pubmed:meshHeading | pubmed-meshheading:1001973-... | lld:pubmed |
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| pubmed-article:1001973 | pubmed:meshHeading | pubmed-meshheading:1001973-... | lld:pubmed |
| pubmed-article:1001973 | pubmed:meshHeading | pubmed-meshheading:1001973-... | lld:pubmed |
| pubmed-article:1001973 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:1001973 | pubmed:articleTitle | Complement fixing hepatitis B core antigen immune complexes in the liver of patients with HBs antigen positive chronic disease. | lld:pubmed |
| pubmed-article:1001973 | pubmed:publicationType | Journal Article | lld:pubmed |
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