| pubmed-article:9951689 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C0684249 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C2347610 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C0079419 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C0021044 | lld:lifeskim |
| pubmed-article:9951689 | lifeskim:mentions | umls-concept:C0205197 | lld:lifeskim |
| pubmed-article:9951689 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9951689 | pubmed:dateCreated | 1999-6-4 | lld:pubmed |
| pubmed-article:9951689 | pubmed:abstractText | In this study the entire p53 complementary DNA has been sequenced in 20 non-small cell lung carcinomas (NSCLC) and the results correlated with chemosensitivity, immunohistochemistry and clinical data. Ten patients had mutations in p53, 8 missense mutations and 2 nonsense mutations. The method discovered two mutations never described previously and two other mutations that have never been described before in connection with NSCLC tumours. Chemosensitivity data, according to a short-term assay (FMCA), indicated that tumours with p53 mutation were more resistant to cisplatin and cyclophosphamide. Immunohistochemical studied demonstrated a 70% concordance between over-expression of p53 protein and mutation in p53. No conclusions or trends could be drawn from the immunohistochemical studies of Bcl-2 and Bax. | lld:pubmed |
| pubmed-article:9951689 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9951689 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9951689 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9951689 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9951689 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9951689 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9951689 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9951689 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:9951689 | pubmed:issn | 1357-0560 | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:LambertFF | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:InganäsMM | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:GustafssonGG | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:BrodieDD | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:KraazWW | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:WageniusGG | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:BergqvistMM | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:BrattströmDD | lld:pubmed |
| pubmed-article:9951689 | pubmed:author | pubmed-author:ScheibenflugL... | lld:pubmed |
| pubmed-article:9951689 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9951689 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:9951689 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9951689 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9951689 | pubmed:pagination | 255-61 | lld:pubmed |
| pubmed-article:9951689 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:9951689 | pubmed:meshHeading | pubmed-meshheading:9951689-... | lld:pubmed |
| pubmed-article:9951689 | pubmed:meshHeading | pubmed-meshheading:9951689-... | lld:pubmed |
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| pubmed-article:9951689 | pubmed:meshHeading | pubmed-meshheading:9951689-... | lld:pubmed |
| pubmed-article:9951689 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9951689 | pubmed:articleTitle | Complete sequence of p53 gene in 20 patients with lung cancer: comparison with chemosensitivity and immunohistochemistry. | lld:pubmed |
| pubmed-article:9951689 | pubmed:affiliation | Department of Oncology, Uppsala Akademiska Hospital, Uppsala University, Sweden. | lld:pubmed |
| pubmed-article:9951689 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9951689 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:9951689 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9951689 | lld:pubmed |
