| pubmed-article:9930402 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9930402 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:9930402 | lifeskim:mentions | umls-concept:C0042874 | lld:lifeskim |
| pubmed-article:9930402 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:9930402 | lifeskim:mentions | umls-concept:C2612541 | lld:lifeskim |
| pubmed-article:9930402 | lifeskim:mentions | umls-concept:C0243144 | lld:lifeskim |
| pubmed-article:9930402 | lifeskim:mentions | umls-concept:C0050486 | lld:lifeskim |
| pubmed-article:9930402 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:9930402 | pubmed:dateCreated | 1999-3-30 | lld:pubmed |
| pubmed-article:9930402 | pubmed:abstractText | The effects of vitamin E on cholesteryl ester (CE) metabolism in J774 cells were examined. Pretreatment of J774 cells with vitamin E at concentrations above 50 microM significantly decreased acetylated low density lipoprotein (LDL)-induced incorporation of [14C]oleate into CE in cells in a dose-dependent manner. This was partly due to vitamin E also significantly inhibiting the uptake of [3H]CE-labeled acetylated LDL by J774 cells. A trend existed toward suppression of acyl-CoA:cholesterol acyltransferase (ACAT) activity in the cell lysate at high vitamin E concentration, but there was no effect on hydrolysis of CE. These data indicate that vitamin E reduces the uptake of modified LDL and suppresses ACAT activity, resulting in less cholesterol esterification in macrophages: a novel mechanism underlying the antiatherogenic properties of vitamin E. | lld:pubmed |
| pubmed-article:9930402 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9930402 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9930402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9930402 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9930402 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:9930402 | pubmed:issn | 0024-4201 | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:NakamuraHH | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:ItoTT | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:HigashiKK | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:IshikawaTT | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:NakajimaKK | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:YamashitaTT | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:ShigaTT | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:NestelPP | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:SuzukawaMM | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:NishiwakiMM | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:AyaoriMM | lld:pubmed |
| pubmed-article:9930402 | pubmed:author | pubmed-author:YonemuraAA | lld:pubmed |
| pubmed-article:9930402 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9930402 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:9930402 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9930402 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9930402 | pubmed:pagination | 1169-75 | lld:pubmed |
| pubmed-article:9930402 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:meshHeading | pubmed-meshheading:9930402-... | lld:pubmed |
| pubmed-article:9930402 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9930402 | pubmed:articleTitle | Vitamin E reduces cholesterol esterification and uptake of acetylated low density lipoprotein in macrophages. | lld:pubmed |
| pubmed-article:9930402 | pubmed:affiliation | First Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan. hideki.shige@baker.edu.au | lld:pubmed |
| pubmed-article:9930402 | pubmed:publicationType | Journal Article | lld:pubmed |
