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pubmed-article:9925439pubmed:abstractTextDesymmerization of symmetric FTY720 by substitution of different alkyl groups for one of the prochiral hydroxymethyl groups was performed. The size of the alkyl groups and the absolute configuration at quaternary carbon were important on immunosuppressive activity.lld:pubmed
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pubmed-article:9925439pubmed:articleTitleSynthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720.lld:pubmed
pubmed-article:9925439pubmed:affiliationResearch Laboratories, Yoshitomi Pharmaceutical Industries, Ltd., Saitama, Japan.lld:pubmed
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