| pubmed-article:991463 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0011616 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0033809 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0038856 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0011570 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:991463 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:991463 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:991463 | pubmed:dateCreated | 1977-1-28 | lld:pubmed |
| pubmed-article:991463 | pubmed:abstractText | Pseudomonas aeruginosa infection depresses contact sensitivity to 2-phenyl-4-ethoximethylene-oxazolone (oxazolone), and enhances the antibody response to sheep erythrocytes (SRBC) in the mouse. Anti-oxazolone antibody titres were found not to be significantly different in infected and uninfected animals; thus, the major circulating classes of antibodies do not seem to be responsibile for the observed depression of skin reactivity. Low dose (20 mg/Kg) cyclophosphamide (CY) pretreatment induced a further potentiation of antibody response to SRBC, and prevented depression of contact sensitivity in infected mice. On the other hand, when infected animals were pretreated with high doses (200 mg/Kg) of CY, antibody production was completely suppressed, whereas contact sensitivity was unaffected. Since CY treatment is known to selectively inhibit B lymphocytes, and since it can abrogate the infection-induced depression of reactivity to oxazolone, it is suggested that suppressor cells, which may have B-cell characteristics, are stimulated during P. aeruginosa infection in the mouse. | lld:pubmed |
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| pubmed-article:991463 | pubmed:language | eng | lld:pubmed |
| pubmed-article:991463 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:991463 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:991463 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:991463 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:991463 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:991463 | pubmed:author | pubmed-author:FerranniniEE | lld:pubmed |
| pubmed-article:991463 | pubmed:author | pubmed-author:FalconeGG | lld:pubmed |
| pubmed-article:991463 | pubmed:author | pubmed-author:CampaMM | lld:pubmed |
| pubmed-article:991463 | pubmed:author | pubmed-author:GarzelliCC | lld:pubmed |
| pubmed-article:991463 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:991463 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:991463 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:991463 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:991463 | pubmed:pagination | 355-62 | lld:pubmed |
| pubmed-article:991463 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:991463 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:991463 | pubmed:articleTitle | Evidence for suppressor cell activity associated with depression of contact sensitivity in Pseudomonas aeruginosa infected mice. | lld:pubmed |
| pubmed-article:991463 | pubmed:publicationType | Journal Article | lld:pubmed |
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