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pubmed-article:9873605pubmed:abstractTextA series of alpha-terthiophene derivatives were prepared and their protein kinase C inhibitory activity were evaluated. The aldehyde derivatives were most potent inhibitors (IC50 < 1 microM). alpha-Terthiophene monoaldehyde was inactive in the inhibitions of protein kinase A, mitogen activated protein kinase and protein tyrosine kinase.lld:pubmed
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pubmed-article:9873605pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:9873605pubmed:articleTitleNovel protein kinase C inhibitors: alpha-terthiophene derivatives.lld:pubmed
pubmed-article:9873605pubmed:affiliationDepartment of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907-1333, USA.lld:pubmed
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