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pubmed-article:9871780pubmed:abstractTextMonocyclic beta-lactams have been identified as potent and selective inhibitors of the human cytomegalovirus protease (HCMV) N(o). Two series of these inhibitors are described, a peptidyl series of compounds and non-peptidic molecules featuring lower molecular weights. The SAR work that lead to the discovery of these inhibitors, together with their synthesis is also disclosed.lld:pubmed
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pubmed-article:9871780pubmed:articleTitleInhibition of human cytomegalovirus protease N(o) with monocyclic beta-lactams.lld:pubmed
pubmed-article:9871780pubmed:affiliationBio-Méga Research Division, Boehringer Ingelheim (Canada) Ltd, Laval, Québec, Canada.lld:pubmed
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