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pubmed-article:9871771pubmed:abstractTextThe novel 3-methoxycarbonyl-2-trifluoromethylcyclopropapyrroloindole (MCTFCPI) bisalkylators were synthesized and their antitumor activity was evaluated. Among these derivatives, 7f in which two MCTFCPI moieties are connected with a 5,5'-bis(2-carbonyl-1H-indole) group, was found to exhibit more prominent cytotoxicity and antitumor activity than U-77,779 (bizelesin) (2).lld:pubmed
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pubmed-article:9871771pubmed:articleTitleThe novel cyclopropapyrroloindole(CPI) bisalkylators bearing methoxycarbonyl and trifluoromethyl groups.lld:pubmed
pubmed-article:9871771pubmed:affiliationCentral Research Laboratories, Kyorin Pharmaceutical Co. Ltd., Tochigi, Japan.lld:pubmed
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