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pubmed-article:9871667pubmed:abstractTextThe synthesis of LIAZAL (compound 9, R085246) is described. LIAZAL inhibits all-trans-retinoic acid metabolism and thereby exerts retinoid-like effects in vivo.lld:pubmed
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pubmed-article:9871667pubmed:articleTitleSynthesis of LIAZAL, a retinoic acid metabolism blocking agent (RAMBA) with potential clinical applications in oncology and dermatology.lld:pubmed
pubmed-article:9871667pubmed:affiliationDepartment of Medicinal Chemistry, Janssen Research Foundation, Beerse, Belgium. efreyne@janbe.jnj.comlld:pubmed
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