| pubmed-article:986393 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C0008046 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C0013765 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C0003483 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C0178576 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
| pubmed-article:986393 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
| pubmed-article:986393 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:986393 | pubmed:dateCreated | 1976-11-1 | lld:pubmed |
| pubmed-article:986393 | pubmed:abstractText | Aortas of 13-day-old chick embryo were labeled for 0.5 hr with [14C]lysine and subjected to a serial extraction after chase for 1-24 hr with [12C]lysine. Substantial radioactivity was found in insoluble elastin after 3 hr chase. The effect of beta-amino-propionitrile on labeling with [14C]lysine was also examined. Each fraction was hydrolyzed and applied to a short column on an amino acid analyzer. Radioactivity was found in desmosine and isodesmosine of insoluble elastin as early as 1 hr after the beginning of chase. The radioactivity increased rapidly at 2 hr and very slowly thereafter. A large count, which was separated into five peaks on a long column, was observed in other lysine derivatives at 2 hr and increased steadily up to 24 hr, while the lysine count decreased from 1 : 0.5 to 1 : 6 against lysine derivatives and from 1 : 0.04 to 1 : 0.9 against quarter-desmosine after 24 hr. The oxidation of lysine residues incorporated during the 0.5 hr pulse was almost completed during the first 1 hr of chase, and these oxidized residues were incorporated into crosslinks during the following 1 hr. It is suggested that poorly crosslinked elastin accumulated in the soluble fractions. The presence of crosslinking derived from lysine residues was also indicated in the microfibril fraction. | lld:pubmed |
| pubmed-article:986393 | pubmed:language | eng | lld:pubmed |
| pubmed-article:986393 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:986393 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:986393 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:986393 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:986393 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:986393 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:986393 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:986393 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:986393 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:986393 | pubmed:issn | 0021-924X | lld:pubmed |
| pubmed-article:986393 | pubmed:author | pubmed-author:KanamoriMM | lld:pubmed |
| pubmed-article:986393 | pubmed:author | pubmed-author:MiyoshiMM | lld:pubmed |
| pubmed-article:986393 | pubmed:author | pubmed-author:RosenbloomJJ | lld:pubmed |
| pubmed-article:986393 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:986393 | pubmed:volume | 79 | lld:pubmed |
| pubmed-article:986393 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:986393 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:986393 | pubmed:pagination | 1235-43 | lld:pubmed |
| pubmed-article:986393 | pubmed:dateRevised | 2007-12-19 | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-A... | lld:pubmed |
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| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-P... | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-C... | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-E... | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-T... | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-P... | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-M... | lld:pubmed |
| pubmed-article:986393 | pubmed:meshHeading | pubmed-meshheading:986393-B... | lld:pubmed |
| pubmed-article:986393 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:986393 | pubmed:articleTitle | Synthesis of elastin. A rapid formation of lysine-derived crosslinks by chick embryo aorta. | lld:pubmed |
| pubmed-article:986393 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:986393 | lld:pubmed |
