| pubmed-article:9861639 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9861639 | lifeskim:mentions | umls-concept:C1424914 | lld:lifeskim |
| pubmed-article:9861639 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9861639 | lifeskim:mentions | umls-concept:C1521797 | lld:lifeskim |
| pubmed-article:9861639 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:9861639 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:9861639 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9861639 | pubmed:dateCreated | 1999-3-29 | lld:pubmed |
| pubmed-article:9861639 | pubmed:abstractText | In a family study involving 83 probands with periodic catatonia a subtype of DSM IIIR schizophrenia, we reported an age-specific morbidity risk of 26.9% in first-degree relatives with homotypical psychoses and genetic anticipation indicating a possible major gene effect. Paternal transmission was associated with a trend for a younger age at onset in probands compared to that observed in the case of maternal transmission (P = 0.099). If this can be confirmed in a larger sample and then replicated, there would be evidence for the occurrence of a parent-of-origin effect. Such an observation may indicate that a paternally imprinted locus acts on periodic catatonia. Among the non-genetic mechanisms that may modify the penetrance of the disease, paternal affection did lead to a decrease in male offspring (P = 0.007) and maternal affection showed an increased frequency of non-affected male offspring (P = 0.021). We therefore propose that parent-of-origin effects as well as prenatal mortality and psychosocial factors need further investigation in the periodic catatonia subtype of schizophrenia. | lld:pubmed |
| pubmed-article:9861639 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9861639 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9861639 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9861639 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9861639 | pubmed:issn | 0955-8829 | lld:pubmed |
| pubmed-article:9861639 | pubmed:author | pubmed-author:BeckmannHH | lld:pubmed |
| pubmed-article:9861639 | pubmed:author | pubmed-author:FranzenHH | lld:pubmed |
| pubmed-article:9861639 | pubmed:author | pubmed-author:HaubitzII | lld:pubmed |
| pubmed-article:9861639 | pubmed:author | pubmed-author:StöberGG | lld:pubmed |
| pubmed-article:9861639 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9861639 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:9861639 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9861639 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9861639 | pubmed:pagination | 213-9 | lld:pubmed |
| pubmed-article:9861639 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:meshHeading | pubmed-meshheading:9861639-... | lld:pubmed |
| pubmed-article:9861639 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9861639 | pubmed:articleTitle | Parent-of-origin effect and evidence for differential transmission in periodic catatonia. | lld:pubmed |
| pubmed-article:9861639 | pubmed:affiliation | Department of Psychiatry, University of Würzburg, Germany. nerk105@rzkli.uni-wuerzburg.de | lld:pubmed |
| pubmed-article:9861639 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9861639 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9861639 | lld:pubmed |
