Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor Nalpha-(4-amino-4-deoxypteroyl)-Ndelta-hemiphthaloyl- L-ornithine (PT523).

Source:http://linkedlifedata.com/resource/pubmed/id/9857098

J. Med. Chem. 1998 Dec 17 41 26 5310-9

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9857098