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pubmed-article:9821162pubmed:abstractTextThis report examines plasma amyloid beta proteins A beta 40 and A beta 42 and apolipoprotein E (apoE) levels and their relationships with age in non-demented older adults with (N = 32) or without the apoE-epsilon 4 allele (N = 94). A beta levels did not differ between the groups whereas the epsilon 4 allele was associated with a significant reduction in plasma apoE. In subjects with the epsilon 4 allele, increasing age was associated with significant reduction in plasma A beta 40. Subjects without the epsilon 4 allele showed a significant positive correlation between A beta 40 and A beta 42 levels. There was also a significant correlation between plasma A beta 40 and apoE levels in all subjects.lld:pubmed
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pubmed-article:9821162pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:9821162pubmed:articleTitleDecreases in plasma A beta 1-40 levels with aging in non-demented elderly with ApoE-epsilon 4 allele.lld:pubmed
pubmed-article:9821162pubmed:affiliationNathan S. Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA. POMARA@nki.rfmh.orglld:pubmed
pubmed-article:9821162pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9821162pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed