| pubmed-article:9813139 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0125090 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0025219 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0085416 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C0522510 | lld:lifeskim |
| pubmed-article:9813139 | lifeskim:mentions | umls-concept:C1292733 | lld:lifeskim |
| pubmed-article:9813139 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9813139 | pubmed:dateCreated | 1998-12-10 | lld:pubmed |
| pubmed-article:9813139 | pubmed:abstractText | Effects of melatonin priming of neutrophils and subsequent increase of phorbol 12-miristate 13-acetate stimulated respiratory burst were investigated on the modulation of L-selectin shedding and MAC-1 upregulation. Respiratory burst related H2O2 production and adhesion molecule expression were quantified by flow cytometry. Phorbol 12-miristate 13-acetate dose dependence of intracellular oxidation and adhesion molecule expression showed no relationship between respiratory burst intensity and MAC-1 expression or L-selectin shedding. Treatment of cells with 12.5 nM phorbol 12-miristate 13-acetate resulted in less than 20% of the respiratory burst response, however it induced 91.7% of total MAC-1 expression and 62.8% of L-selectin shedding. Melatonin priming experiments showed also no connection between the extent of respiratory burst and MAC-1 expression, however melatonin priming almost completely prevented L-selectin down-regulation elicited by phorbol 12-miristate 13-acetate, without affecting MAC-1 expression. It is suggested that melatonin may inhibit metalloproteases responsible for L-selectin cleavage. | lld:pubmed |
| pubmed-article:9813139 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9813139 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9813139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9813139 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9813139 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:9813139 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:9813139 | pubmed:author | pubmed-author:PieriCC | lld:pubmed |
| pubmed-article:9813139 | pubmed:author | pubmed-author:MoroniFF | lld:pubmed |
| pubmed-article:9813139 | pubmed:author | pubmed-author:KesterRR | lld:pubmed |
| pubmed-article:9813139 | pubmed:author | pubmed-author:DamjanovichSS | lld:pubmed |
| pubmed-article:9813139 | pubmed:author | pubmed-author:RecchioneVV | lld:pubmed |
| pubmed-article:9813139 | pubmed:author | pubmed-author:MarcheselliFF | lld:pubmed |
| pubmed-article:9813139 | pubmed:copyrightInfo | Copyright 1998 Academic Press. | lld:pubmed |
| pubmed-article:9813139 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9813139 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:9813139 | pubmed:volume | 252 | lld:pubmed |
| pubmed-article:9813139 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9813139 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9813139 | pubmed:pagination | 20-4 | lld:pubmed |
| pubmed-article:9813139 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:meshHeading | pubmed-meshheading:9813139-... | lld:pubmed |
| pubmed-article:9813139 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9813139 | pubmed:articleTitle | Melatonin increases the intensity of respiratory burst and prevents L-selectin shedding in human neutrophils in vitro. | lld:pubmed |
| pubmed-article:9813139 | pubmed:affiliation | "Nino Masera" Gerontology Research Department, I.N.R.C.A., Ancona, 60121, Italy. | lld:pubmed |
| pubmed-article:9813139 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9813139 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:9813139 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9813139 | lld:pubmed |
