pubmed-article:9802014 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C0006837 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C0015576 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C0680022 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C1327616 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C2717969 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
pubmed-article:9802014 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
pubmed-article:9802014 | pubmed:dateCreated | 1999-1-13 | lld:pubmed |
pubmed-article:9802014 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9802014 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9802014 | pubmed:abstractText | Secreted aspartic proteinases (Saps) contribute to the virulence of Candida albicans in systemic animal models of infection. Seven genes encoding Saps (SAP1-SAP7) have been identified to date but evidence suggested the existence of additional SAP genes. The screening of a C. albicans lambda EMBL3 genomic library for the presence of other SAP genes was undertaken. Two new genes, SAP8 and SAP9, were isolated. The N-terminal amino acid sequence deduced from SAP8 downstream of a Kex2p-like cleavage site corresponds to the N-terminal amino acid sequence of the 41 kDa Sap isolated and characterized previously. SAP8 mRNA was expressed preferentially in yeasts at 25 degrees C after 6 and 9 h growth in BSA-containing medium. SAP9 encodes an aspartic proteinase with a Kex2p-like cleavage site and contains a putative glycophosphatidylinositol-anchor signal at the C-terminus. Although the SAP9 gene product has not yet been isolated from cultures of C. albicans, transcripts of SAP9 were observed preferentially in later growth phases when SAP8 expression had decreased. | lld:pubmed |
pubmed-article:9802014 | pubmed:language | eng | lld:pubmed |
pubmed-article:9802014 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9802014 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9802014 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9802014 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9802014 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9802014 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9802014 | pubmed:month | Oct | lld:pubmed |
pubmed-article:9802014 | pubmed:issn | 1350-0872 | lld:pubmed |
pubmed-article:9802014 | pubmed:author | pubmed-author:HessDD | lld:pubmed |
pubmed-article:9802014 | pubmed:author | pubmed-author:MonodMM | lld:pubmed |
pubmed-article:9802014 | pubmed:author | pubmed-author:SanglardDD | lld:pubmed |
pubmed-article:9802014 | pubmed:author | pubmed-author:HublEE | lld:pubmed |
pubmed-article:9802014 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9802014 | pubmed:volume | 144 ( Pt 10) | lld:pubmed |
pubmed-article:9802014 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9802014 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9802014 | pubmed:pagination | 2731-7 | lld:pubmed |
pubmed-article:9802014 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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pubmed-article:9802014 | pubmed:meshHeading | pubmed-meshheading:9802014-... | lld:pubmed |
pubmed-article:9802014 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9802014 | pubmed:articleTitle | Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans. | lld:pubmed |
pubmed-article:9802014 | pubmed:affiliation | Service de Dermatologie (DHURDV), Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Michel.Monod@chuv.hospvd.ch | lld:pubmed |
pubmed-article:9802014 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9802014 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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