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pubmed-article:9794837pubmed:abstractTextCD8+ cytotoxic lymphocytes, natural killer cells and lymphokine-activated killer cells depend primarily on the perforin/granzyme system to kill their targets, while CD4+ T cells utilize Fas and other mechanisms to induce cell death. The molecular mechanisms used by these pathways to induce target cell apoptosis may converge on common death substrates.lld:pubmed
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pubmed-article:9794837pubmed:articleTitleHow do cytotoxic lymphocytes kill their targets?lld:pubmed
pubmed-article:9794837pubmed:affiliationDepartment of Medicine, Washington University School of Medicine, St Louis, MO 63110-1093, USA.lld:pubmed
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