| pubmed-article:9757563 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0041370 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0063482 | lld:lifeskim |
| pubmed-article:9757563 | lifeskim:mentions | umls-concept:C0758375 | lld:lifeskim |
| pubmed-article:9757563 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:9757563 | pubmed:dateCreated | 1998-10-29 | lld:pubmed |
| pubmed-article:9757563 | pubmed:abstractText | (-)-Indolactam-V (1) without a hydrophobic chain at positions 6 and 7 of the indole ring is a weak tumor promoter compared with teleocidin Bs. To investigate the effects of the hydrophobic substituent at position 6 of teleocidin Bs, we synthesized (-)-6-n-octyl-indolactam-V (2) by a palladium-catalyzed coupling reaction from (-)-6-bromo-indolactam-V (7) which had been obtained by microbial conversion with Streptoverticillium blastmyceticum NA34-17 as the key step. (-)-7-n-Octyl-indolactam-V (3) with potent biological activities comparable to those of teleocidin Bs was similarly synthesized from (-)-7-bromo-indolactam-V as a positive control. Compound 2 showed similar biological activities to those of 3, indicating that the effect of the hydrophobic substituent at position 6 of 1 was identical to that at position 7. | lld:pubmed |
| pubmed-article:9757563 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9757563 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9757563 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9757563 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9757563 | pubmed:issn | 0916-8451 | lld:pubmed |
| pubmed-article:9757563 | pubmed:author | pubmed-author:HayashiHH | lld:pubmed |
| pubmed-article:9757563 | pubmed:author | pubmed-author:NakagawaYY | lld:pubmed |
| pubmed-article:9757563 | pubmed:author | pubmed-author:NakamuraYY | lld:pubmed |
| pubmed-article:9757563 | pubmed:author | pubmed-author:IrieKK | lld:pubmed |
| pubmed-article:9757563 | pubmed:author | pubmed-author:OhigashiHH | lld:pubmed |
| pubmed-article:9757563 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9757563 | pubmed:volume | 62 | lld:pubmed |
| pubmed-article:9757563 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9757563 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9757563 | pubmed:pagination | 1568-73 | lld:pubmed |
| pubmed-article:9757563 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:9757563 | pubmed:meshHeading | pubmed-meshheading:9757563-... | lld:pubmed |
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| pubmed-article:9757563 | pubmed:meshHeading | pubmed-meshheading:9757563-... | lld:pubmed |
| pubmed-article:9757563 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9757563 | pubmed:articleTitle | Synthesis and biological activities of (-)-6-n-octyl-indolactam-V, a new potent analogue of the tumor promoter (-)-indolactam-V. | lld:pubmed |
| pubmed-article:9757563 | pubmed:affiliation | Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan. | lld:pubmed |
| pubmed-article:9757563 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9757563 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
