| pubmed-article:9729041 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9729041 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:9729041 | lifeskim:mentions | umls-concept:C0005516 | lld:lifeskim |
| pubmed-article:9729041 | lifeskim:mentions | umls-concept:C0879590 | lld:lifeskim |
| pubmed-article:9729041 | lifeskim:mentions | umls-concept:C0017255 | lld:lifeskim |
| pubmed-article:9729041 | lifeskim:mentions | umls-concept:C0303920 | lld:lifeskim |
| pubmed-article:9729041 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9729041 | pubmed:dateCreated | 1998-9-22 | lld:pubmed |
| pubmed-article:9729041 | pubmed:abstractText | Production of interleukin (IL)-2 by T lymphocytes is one of the earliest events during immune response. A mutant mouse strain was generated by replacing the IL-2 gene with a cDNA encoding green fluorescent protein (GFP). In this model, GFP fluorescence is readily detectable upon T cell activation and is mostly coexpressed with IL-2 at the single cell level. Thus, individual activated T cells can express the IL-2 gene biallelically. Upon stimulation through the T cell antigen receptor, CD4+ cells separate into distinct GFP+ and GFP- populations, both of which are capable of differentiating into either Th1 or Th2 effectors. These mice allow noninvasive detection of IL-2 production by single cells and analysis of the subsequent differentiative fate of these cells as an immune response develops. | lld:pubmed |
| pubmed-article:9729041 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9729041 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9729041 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9729041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9729041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9729041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9729041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9729041 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9729041 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9729041 | pubmed:issn | 1074-7613 | lld:pubmed |
| pubmed-article:9729041 | pubmed:author | pubmed-author:FOYJ LJL | lld:pubmed |
| pubmed-article:9729041 | pubmed:author | pubmed-author:NaramuraMM | lld:pubmed |
| pubmed-article:9729041 | pubmed:author | pubmed-author:HoR DRD | lld:pubmed |
| pubmed-article:9729041 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9729041 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:9729041 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9729041 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9729041 | pubmed:pagination | 209-16 | lld:pubmed |
| pubmed-article:9729041 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:9729041 | pubmed:meshHeading | pubmed-meshheading:9729041-... | lld:pubmed |
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| pubmed-article:9729041 | pubmed:meshHeading | pubmed-meshheading:9729041-... | lld:pubmed |
| pubmed-article:9729041 | pubmed:meshHeading | pubmed-meshheading:9729041-... | lld:pubmed |
| pubmed-article:9729041 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9729041 | pubmed:articleTitle | Mice with a fluorescent marker for interleukin 2 gene activation. | lld:pubmed |
| pubmed-article:9729041 | pubmed:affiliation | Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA. | lld:pubmed |
| pubmed-article:9729041 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9729041 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:16183 | entrezgene:pubmed | pubmed-article:9729041 | lld:entrezgene |
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