| pubmed-article:9719630 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0024299 | lld:lifeskim |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0006764 | lld:lifeskim |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0085110 | lld:lifeskim |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0086661 | lld:lifeskim |
| pubmed-article:9719630 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:9719630 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:9719630 | pubmed:dateCreated | 1998-9-14 | lld:pubmed |
| pubmed-article:9719630 | pubmed:abstractText | Epstein-Barr virus (EBV) has been associated with several malignant processes in man, most notably Burkitt lymphoma in previously healthy individuals and lesions resembling large cell non-Hodgkin lymphomas in organ transplant recipients. Mice with the severe combined immunodeficiency phenotype (SCID mice) are exquisitely susceptible to the development of EBV-associated lymphoproliferative lesions following the intraperitoneal (ip) inoculation of EBV-infected human lymphocytes. Recently, we reported that EBV-infected marmoset lymphocytes do not form lymphomas in SCID mice following ip injection, while human lymphocytes infected with the same EBV strains do. On the assumption that the EBV-infected marmoset cells were lacking a factor necessary for tumor formation, we transfected a plasmid containing c-myc into EBV-infected marmoset cells (B95-8, FF41, and W91 cells). Despite expression of the c-myc protein as determined by immunoblot and flow cytometry when probed with a monoclonal antibody, no increase over baseline lesion development was seen in SCID mice inoculated with 5 x 10(6) c-myc-expressing marmoset lymphoblastoid cells. Thus, cells that express c-myc and harbor EBV are not sufficient to form lymphomas in certain immunocompromised hosts. | lld:pubmed |
| pubmed-article:9719630 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9719630 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9719630 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9719630 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9719630 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9719630 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9719630 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:9719630 | pubmed:issn | 1096-7192 | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:VariakojisDD | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:NewmanMM | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:BendelEE | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:KatsB SBS | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:O'GormanM RMR | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:SalimoHH | lld:pubmed |
| pubmed-article:9719630 | pubmed:author | pubmed-author:PoupkoEE | lld:pubmed |
| pubmed-article:9719630 | pubmed:copyrightInfo | Copyright 1998 Academic Press. | lld:pubmed |
| pubmed-article:9719630 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9719630 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:9719630 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9719630 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9719630 | pubmed:pagination | 205-12 | lld:pubmed |
| pubmed-article:9719630 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9719630 | pubmed:meshHeading | pubmed-meshheading:9719630-... | lld:pubmed |
| pubmed-article:9719630 | pubmed:meshHeading | pubmed-meshheading:9719630-... | lld:pubmed |
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| pubmed-article:9719630 | pubmed:meshHeading | pubmed-meshheading:9719630-... | lld:pubmed |
| pubmed-article:9719630 | pubmed:meshHeading | pubmed-meshheading:9719630-... | lld:pubmed |
| pubmed-article:9719630 | pubmed:meshHeading | pubmed-meshheading:9719630-... | lld:pubmed |
| pubmed-article:9719630 | pubmed:meshHeading | pubmed-meshheading:9719630-... | lld:pubmed |
| pubmed-article:9719630 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9719630 | pubmed:articleTitle | Epstein-Barr virus-infected marmoset cells transfected with c-myc do not form lymphomas in mice with severe combined immunodeficiency. | lld:pubmed |
| pubmed-article:9719630 | pubmed:affiliation | Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois, USA. | lld:pubmed |
| pubmed-article:9719630 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9719630 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
