| pubmed-article:9707175 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9707175 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:9707175 | lifeskim:mentions | umls-concept:C1801960 | lld:lifeskim |
| pubmed-article:9707175 | lifeskim:mentions | umls-concept:C0071216 | lld:lifeskim |
| pubmed-article:9707175 | lifeskim:mentions | umls-concept:C0380603 | lld:lifeskim |
| pubmed-article:9707175 | lifeskim:mentions | umls-concept:C0600210 | lld:lifeskim |
| pubmed-article:9707175 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:9707175 | pubmed:dateCreated | 1998-9-2 | lld:pubmed |
| pubmed-article:9707175 | pubmed:abstractText | The spindle-shaped cell line TTB was recently isolated from highly vascularized skin lesions of BKV/HIV-1 tat transgenic mice and shown to possess an autocrine loop for hepatocyte growth factor (HGF). We show that fibroblast growth factor-2 (FGF-2) stimulates TTB cell migration and promotes polarization of uPAR at the leading edge of migrating cells. FGF-stimulated TTB cells presented the typical migratory phenotype, with a triangular cell shape and concomitant breakdown of actin stress fibers and smooth muscle-specific actin isoform. FGF-2-stimulated migration was blocked by antibodies against urokinase-type plasminogen activator (uPA) or uPA receptor (uPAR) and by neutralizing anti-HGF antibodies. The latter also inhibited uPAR relocalization at the cell surface of FGF-2-treated TTB cells. This points to a crosstalk between FGF-2 and HGF that might mediate TTB cell migration by modulating the localization of cell surface uPAR. | lld:pubmed |
| pubmed-article:9707175 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9707175 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9707175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9707175 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9707175 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9707175 | pubmed:issn | 0892-6638 | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:MontesanoRR | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:PepperM SMS | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:WuZZ | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:SoriaM RMR | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:MaierJ AJA | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:CavallaroUU | lld:pubmed |
| pubmed-article:9707175 | pubmed:author | pubmed-author:Di PaloAA | lld:pubmed |
| pubmed-article:9707175 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9707175 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:9707175 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9707175 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9707175 | pubmed:pagination | 1027-34 | lld:pubmed |
| pubmed-article:9707175 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:meshHeading | pubmed-meshheading:9707175-... | lld:pubmed |
| pubmed-article:9707175 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9707175 | pubmed:articleTitle | FGF-2 stimulates migration of Kaposi's sarcoma-like vascular cells by HGF-dependent relocalization of the urokinase receptor. | lld:pubmed |
| pubmed-article:9707175 | pubmed:affiliation | Department of Biological and Technological Research, San Raffaele Scientific Institute, Milano, Italy. cavallu@dibit.hsr.it | lld:pubmed |
| pubmed-article:9707175 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9707175 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9707175 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9707175 | lld:pubmed |
