Linked Life Data

9693045

Source:http://linkedlifedata.com/resource/pubmed/id/9693045

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pubmed-article:9693045pubmed:abstractTextSM22alpha (TAGLN) is one of the earliest markers of differentiated smooth muscle, being expressed exclusively in the smooth muscle cells of adult tissues and transiently in embryonic skeletal and cardiac tissues. We have identified and mapped the mouse Tagln gene and a closely related gene, Sm22alpha homolog (Tagln2). The chromosomal localization for Tagln was identified by linkage analysis to distal mouse chromosome 9 between D9Mit154 and D9Mit330, closely linked to the anchor locus D9Nds10. The localization of Tagln2 was also determined and was found to map between Fcgr2 and D1Mit149 on distal mouse chromosome 1. This localization is homologous to a region of human 1q21-q25 to which an EST representing human TAGLN2 was previously mapped. The two regions, distal mouse chromosome 1 and proximal mouse chromosome 9, and the human regions with conserved synteny (1q21-q25 and 11q22-qter) are believed to be paralogous, reflecting either conserved remnants of duplicated chromosomes or segments of chromosomes during vertebrate evolution.lld:pubmed
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pubmed-article:9693045pubmed:authorpubmed-author:StanierPPlld:pubmed
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pubmed-article:9693045pubmed:authorpubmed-author:MurdochJ NJNlld:pubmed
pubmed-article:9693045pubmed:authorpubmed-author:Abu-HayyehSSlld:pubmed
pubmed-article:9693045pubmed:copyrightInfoCopyright 1998 Academic Press.lld:pubmed
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pubmed-article:9693045pubmed:pagination144-7lld:pubmed
pubmed-article:9693045pubmed:dateRevised2011-11-10lld:pubmed
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pubmed-article:9693045pubmed:year1998lld:pubmed
pubmed-article:9693045pubmed:articleTitleParalogous sm22alpha (Tagln) genes map to mouse chromosomes 1 and 9: further evidence for a paralogous relationship.lld:pubmed
pubmed-article:9693045pubmed:affiliationDivision of Paediatrics, Obstetrics and Gynaecology, Queen Charlotte's and Chelsea Hospital, Goldhawk Road, London, W6 OXG, United Kingdom. pstanier@rpms.ac.uklld:pubmed
pubmed-article:9693045pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9693045pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:9693045pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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