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pubmed-article:9684722pubmed:abstractTextEven though the clinical advantage of biphasic defibrillation waveforms is well documented, the mechanisms that underlie this greater efficacy remain incompletely understood. It is established, though, that the response of relatively refractory cells to the shock is important in determining defibrillation success or failure. We used two computer models of an isolated ventricular cell to test the hypothesis that biphasic stimuli cause a more uniform response than the equivalent monophasic shocks, decreasing the likelihood that fibrillation will be reinduced.lld:pubmed
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pubmed-article:9684722pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:9684722pubmed:articleTitlePostshock potential gradients and dispersion of repolarization in cells stimulated with monophasic and biphasic waveforms.lld:pubmed
pubmed-article:9684722pubmed:affiliationDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.lld:pubmed
pubmed-article:9684722pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9684722pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:9684722pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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