We performed mechanical induction of heterotopic ossification in the quadriceps of the right hind limb of six male and six female sexually mature New Zealand white rabbits of similar size. The effect of sex difference on heterotopic bone was assessed by analyzing plain radiographs of the femur. The results indicate that a male/female sex difference in heterotopic bone formation cannot be demonstrated.
Department of Orthopaedic Surgery and the Orthopaedic Research Laboratories of the Bone & Joint Center, Henry Ford Hospital, Detroit, Mich 48202-2689, USA.
