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pubmed-article:9647171pubmed:abstractTextTo determine the feasibility, toxicity, and potential therapeutic benefits of systemic adoptive immunotherapy, 10 patients with progressive primary or recurrent malignant glioma received this treatment. Adoptive immunotherapy, the transfer of immune T lymphocytes, is capable of mediating the regression of experimental brain tumors in animal models. In animal models, lymph nodes (LNs) that drain the tumor vaccine site are a rich source of tumor-immune T cells.lld:pubmed
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pubmed-article:9647171pubmed:articleTitleSystemic T cell adoptive immunotherapy of malignant gliomas.lld:pubmed
pubmed-article:9647171pubmed:affiliationDepartment of Neurological Surgery, Center for Surgery Research, The Cleveland Clinic Foundation, Ohio 44195, USA.lld:pubmed
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