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pubmed-article:9642972pubmed:abstractTextWe recorded all-night polysomnograms of four schizophrenic patients with neuroleptic-induced akathisia (NIA) before and during treatment with clonazepam. Also, four non-akathitic schizophrenic patients were recorded all-night polysomnograms as control subjects. Daily treatment with 1.5 to 3 mg clonazepam improved subjective complaints of all the 4 patients with NIA. Three of 4 patients with NIA exhibited periodic limb movements (PLM) on bilateral legs, but none of 4 control subjects showed PLM. Total number of PLM and PLM per hour decreased during clonazepam treatment. Moreover, mean inter-movement intervals of PLM of 3 patients were prolonged on bilateral legs. NIA might change its feature as PLM during night sleep.lld:pubmed
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pubmed-article:9642972pubmed:articleTitlePeriodic limb movement disorder in neuroleptic-induced akathisia.lld:pubmed
pubmed-article:9642972pubmed:affiliationNishimatsu Clinic, Hyogo, Japan.lld:pubmed
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