| pubmed-article:9630218 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C0337611 | lld:lifeskim |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C0014597 | lld:lifeskim |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C0596901 | lld:lifeskim |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C0887882 | lld:lifeskim |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C2611830 | lld:lifeskim |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C0011209 | lld:lifeskim |
| pubmed-article:9630218 | lifeskim:mentions | umls-concept:C1521902 | lld:lifeskim |
| pubmed-article:9630218 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:9630218 | pubmed:dateCreated | 1998-7-6 | lld:pubmed |
| pubmed-article:9630218 | pubmed:abstractText | In budding yeast, the Sec6/8p complex is essential for generating cell polarity by specifying vesicle delivery to the bud tip. We show that Sec6/8 homologs are components of a cytosolic, approximately 17S complex in nonpolarized MDCK epithelial cells. Upon initiation of calcium-dependent cell-cell adhesion, approximately 70% of Sec6/8 is rapidly (t(1/2) approximately 3-6 hr) recruited to sites of cell-cell contact. In streptolysin-O-permeabilized MDCK cells, Sec8 antibodies inhibit delivery of LDL receptor to the basal-lateral membrane, but not p75NTR to the apical membrane. These results indicate that lateral membrane recruitment of the Sec6/8 complex is a consequence of cell-cell adhesion and is essential for the biogenesis of epithelial cell surface polarity. | lld:pubmed |
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| pubmed-article:9630218 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9630218 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9630218 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9630218 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9630218 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9630218 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9630218 | pubmed:month | May | lld:pubmed |
| pubmed-article:9630218 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:HsuS CSC | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:NelsonW JWJ | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:SchellerR HRH | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:Rodriguez-Bou... | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:YeamanCC | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:GrindstaffK... | lld:pubmed |
| pubmed-article:9630218 | pubmed:author | pubmed-author:Anandasabapat... | lld:pubmed |
| pubmed-article:9630218 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9630218 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:9630218 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:9630218 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9630218 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9630218 | pubmed:pagination | 731-40 | lld:pubmed |
| pubmed-article:9630218 | pubmed:dateRevised | 2011-3-18 | lld:pubmed |
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| pubmed-article:9630218 | pubmed:meshHeading | pubmed-meshheading:9630218-... | lld:pubmed |
| pubmed-article:9630218 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9630218 | pubmed:articleTitle | Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. | lld:pubmed |
| pubmed-article:9630218 | pubmed:affiliation | Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305-5345, USA. | lld:pubmed |
| pubmed-article:9630218 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9630218 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9630218 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:60412 | entrezgene:pubmed | pubmed-article:9630218 | lld:entrezgene |
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