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pubmed-article:9614595pubmed:abstractTextBecause of reported efficacy of combining classes of antidepressants, 25 patients were treated with bupropion in combination with SRI's and venlafaxine. Fifteen patients inadequately responsive to monotherapy received combination treatment; ten patients without residual symptoms received adjunctive bupropion to treat SRI- or venlafaxine-induced side effects. Fourteen subjects (56%) responded, 11 (44%) did not. Twelve of 15 subjects receiving combination treatment to boost the effects of monotherapy responded, while only 2 of 10 subjects receiving combination treatment for side effects responded. Combination therapy was well tolerated even by geriatric and "medically frail" patients.lld:pubmed
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pubmed-article:9614595pubmed:articleTitleUse of bupropion with SRIs and venlafaxine.lld:pubmed
pubmed-article:9614595pubmed:affiliationUniversity of Maryland School of Medicine, Baltimore 21202-2165, USA.lld:pubmed
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