| pubmed-article:9608008 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9608008 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:9608008 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:9608008 | lifeskim:mentions | umls-concept:C0036974 | lld:lifeskim |
| pubmed-article:9608008 | lifeskim:mentions | umls-concept:C0043253 | lld:lifeskim |
| pubmed-article:9608008 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:9608008 | pubmed:issue | 6 Pt 2 | lld:pubmed |
| pubmed-article:9608008 | pubmed:dateCreated | 1998-11-5 | lld:pubmed |
| pubmed-article:9608008 | pubmed:abstractText | Bradykinin (BK) is activated via plasma and/or tissue kallikrein-kinin (K-K) system pathways during hypotension after blunt trauma. The precise role of the K-K system in human subjects has not been defined. We developed a new method for measuring levels of BK in the blood and examined the role of the K-K system in patients with shock after trauma. Eight patients were entered into this study. We measured the levels of a high-molecular-weight kininogen (HMWK), a low-molecular-weight kininogen (LMWK), BK, and (1-5)-BK in the blood of patients in an unstable state (Pre) and a stable state (Post). At Pre, the blood BK level was significantly elevated, the HMWK and LMWK levels were significantly lower, and the (1-5)-BK level was significantly higher than the respective levels at Post. Our data suggest a significant role for the K-K system in the pathogenesis of shock after blunt trauma. This newly developed method for determination of the activation of the plasma K-K system appears to be useful for determining the severity of a trauma. | lld:pubmed |
| pubmed-article:9608008 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9608008 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9608008 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9608008 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:9608008 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:9608008 | pubmed:author | pubmed-author:HirataMM | lld:pubmed |
| pubmed-article:9608008 | pubmed:author | pubmed-author:OhwadaTT | lld:pubmed |
| pubmed-article:9608008 | pubmed:author | pubmed-author:SugimotoKK | lld:pubmed |
| pubmed-article:9608008 | pubmed:author | pubmed-author:KatoriMM | lld:pubmed |
| pubmed-article:9608008 | pubmed:author | pubmed-author:MajimaMM | lld:pubmed |
| pubmed-article:9608008 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9608008 | pubmed:volume | 274 | lld:pubmed |
| pubmed-article:9608008 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9608008 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9608008 | pubmed:pagination | R1556-60 | lld:pubmed |
| pubmed-article:9608008 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:meshHeading | pubmed-meshheading:9608008-... | lld:pubmed |
| pubmed-article:9608008 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9608008 | pubmed:articleTitle | Evidence for a role of kallikrein-P6nin system in patients with shock after blunt trauma. | lld:pubmed |
| pubmed-article:9608008 | pubmed:affiliation | Department of Emergency and Critical Care Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan. | lld:pubmed |
| pubmed-article:9608008 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9608008 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9608008 | lld:pubmed |
