| pubmed-article:9590172 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C1334290 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:9590172 | lifeskim:mentions | umls-concept:C0332453 | lld:lifeskim |
| pubmed-article:9590172 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:9590172 | pubmed:dateCreated | 1998-5-29 | lld:pubmed |
| pubmed-article:9590172 | pubmed:abstractText | Herein we report the generation of mice lacking the ubiquitously expressed Janus kinase, Jak1. Jak1-/- mice are runted at birth, fail to nurse, and die perinatally. Although Jak1-/- cells are responsive to many cytokines, they fail to manifest biologic responses to cytokines that bind to three distinct families of cytokine receptors. These include all class II cytokine receptors, cytokine receptors that utilize the gamma(c) subunit for signaling, and the family of cytokine receptors that depend on the gp130 subunit for signaling. Our results thus demonstrate that Jak1 plays an essential and nonredundant role in promoting biologic responses induced by a select subset of cytokine receptors, including those in which Jak utilization was thought to be nonspecific. | lld:pubmed |
| pubmed-article:9590172 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9590172 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9590172 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9590172 | pubmed:month | May | lld:pubmed |
| pubmed-article:9590172 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:JohnsonE... | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:SchreiberR... | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:WhiteJ MJM | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:PennicaDD | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:YinLL | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:KellH RHR | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:LampeP APA | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:SheehanK CKC | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:MerazM AMA | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:RodinS ASA | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:ArthurC DCD | lld:pubmed |
| pubmed-article:9590172 | pubmed:author | pubmed-author:RileyJ KJK | lld:pubmed |
| pubmed-article:9590172 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9590172 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:9590172 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:9590172 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9590172 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9590172 | pubmed:pagination | 373-83 | lld:pubmed |
| pubmed-article:9590172 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:meshHeading | pubmed-meshheading:9590172-... | lld:pubmed |
| pubmed-article:9590172 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9590172 | pubmed:articleTitle | Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. | lld:pubmed |
| pubmed-article:9590172 | pubmed:affiliation | Center for Immunology and Department of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. | lld:pubmed |
| pubmed-article:9590172 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9590172 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9590172 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:16451 | entrezgene:pubmed | pubmed-article:9590172 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9590172 | lld:pubmed |
