pubmed-article:9582341 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C0524637 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C0007004 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C0245382 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C0444626 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C0043309 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C2699488 | lld:lifeskim |
pubmed-article:9582341 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
pubmed-article:9582341 | pubmed:issue | 21 | lld:pubmed |
pubmed-article:9582341 | pubmed:dateCreated | 1998-6-25 | lld:pubmed |
pubmed-article:9582341 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9582341 | pubmed:abstractText | Galectins are a family of lectins which share similar carbohydrate recognition domains (CRDs) and affinity for small beta-galactosides, but which show significant differences in binding specificity for more complex glycoconjugates. We report here the x-ray crystal structure of the human galectin-3 CRD, in complex with lactose and N-acetyllactosamine, at 2.1-A resolution. This structure represents the first example of a CRD determined from a galectin which does not show the canonical 2-fold symmetric dimer organization. Comparison with the published structures of galectins-1 and -2 provides an explanation for the differences in carbohydrate-binding specificity shown by galectin-3, and for the fact that it fails to form dimers by analogous CRD-CRD interactions. | lld:pubmed |
pubmed-article:9582341 | pubmed:language | eng | lld:pubmed |
pubmed-article:9582341 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9582341 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9582341 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9582341 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:9582341 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9582341 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9582341 | pubmed:month | May | lld:pubmed |
pubmed-article:9582341 | pubmed:issn | 0021-9258 | lld:pubmed |
pubmed-article:9582341 | pubmed:author | pubmed-author:BarondesS HSH | lld:pubmed |
pubmed-article:9582341 | pubmed:author | pubmed-author:LefflerHH | lld:pubmed |
pubmed-article:9582341 | pubmed:author | pubmed-author:RiniJ MJM | lld:pubmed |
pubmed-article:9582341 | pubmed:author | pubmed-author:SeetharamanJJ | lld:pubmed |
pubmed-article:9582341 | pubmed:author | pubmed-author:SlaabyRR | lld:pubmed |
pubmed-article:9582341 | pubmed:author | pubmed-author:KanigsbergAA | lld:pubmed |
pubmed-article:9582341 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9582341 | pubmed:day | 22 | lld:pubmed |
pubmed-article:9582341 | pubmed:volume | 273 | lld:pubmed |
pubmed-article:9582341 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9582341 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9582341 | pubmed:pagination | 13047-52 | lld:pubmed |
pubmed-article:9582341 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:9582341 | pubmed:meshHeading | pubmed-meshheading:9582341-... | lld:pubmed |
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pubmed-article:9582341 | pubmed:meshHeading | pubmed-meshheading:9582341-... | lld:pubmed |
pubmed-article:9582341 | pubmed:meshHeading | pubmed-meshheading:9582341-... | lld:pubmed |
pubmed-article:9582341 | pubmed:meshHeading | pubmed-meshheading:9582341-... | lld:pubmed |
pubmed-article:9582341 | pubmed:meshHeading | pubmed-meshheading:9582341-... | lld:pubmed |
pubmed-article:9582341 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9582341 | pubmed:articleTitle | X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. | lld:pubmed |
pubmed-article:9582341 | pubmed:affiliation | Departments of Molecular and Medical Genetics and Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada. | lld:pubmed |
pubmed-article:9582341 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9582341 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
literatureCitation:2467_958... | literatureCitation:pubmed | pubmed-article:9582341 | lld:drugbank |
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