| pubmed-article:9580671 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C0291147 | lld:lifeskim |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C0663937 | lld:lifeskim |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C0694894 | lld:lifeskim |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C0694895 | lld:lifeskim |
| pubmed-article:9580671 | lifeskim:mentions | umls-concept:C1704222 | lld:lifeskim |
| pubmed-article:9580671 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:9580671 | pubmed:dateCreated | 1998-6-19 | lld:pubmed |
| pubmed-article:9580671 | pubmed:abstractText | Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by a mutation in either the TSC1 or TSC2 tumour suppressor gene. The disease is characterized by a broad phenotypic spectrum that can include seizures, mental retardation, renal dysfunction and dermatological abnormalities. TSC2 encodes tuberin, a putative GTPase activating protein for rap1 and rab5. The TSC1 gene was recently identified and codes for hamartin, a novel protein with no significant homology to tuberin or any other known vertebrate protein. Here, we show that hamartin and tuberin associate physically in vivo and that the interaction is mediated by predicted coiled-coil domains. Our data suggest that hamartin and tuberin function in the same complex rather than in separate pathways. | lld:pubmed |
| pubmed-article:9580671 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9580671 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9580671 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9580671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9580671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9580671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9580671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9580671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9580671 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9580671 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:9580671 | pubmed:issn | 0964-6906 | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:HallerOO | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:SampsonJJ | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:CheadleJJ | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:ReuserAA | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:SnellRR | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:NellistMM | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:van den... | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:9580671 | pubmed:author | pubmed-author:NagelkerkenBB | lld:pubmed |
| pubmed-article:9580671 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9580671 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:9580671 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9580671 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9580671 | pubmed:pagination | 1053-7 | lld:pubmed |
| pubmed-article:9580671 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:meshHeading | pubmed-meshheading:9580671-... | lld:pubmed |
| pubmed-article:9580671 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9580671 | pubmed:articleTitle | Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products. | lld:pubmed |
| pubmed-article:9580671 | pubmed:affiliation | MGC Department of Clinical Genetics, Erasmus University, 3015GE Rotterdam, The Netherlands. | lld:pubmed |
| pubmed-article:9580671 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9580671 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:7248 | entrezgene:pubmed | pubmed-article:9580671 | lld:entrezgene |
| entrez-gene:7249 | entrezgene:pubmed | pubmed-article:9580671 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9580671 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9580671 | lld:pubmed |
