| pubmed-article:9574450 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9574450 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:9574450 | lifeskim:mentions | umls-concept:C0234421 | lld:lifeskim |
| pubmed-article:9574450 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:9574450 | lifeskim:mentions | umls-concept:C1424601 | lld:lifeskim |
| pubmed-article:9574450 | lifeskim:mentions | umls-concept:C0549178 | lld:lifeskim |
| pubmed-article:9574450 | lifeskim:mentions | umls-concept:C0031146 | lld:lifeskim |
| pubmed-article:9574450 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9574450 | pubmed:dateCreated | 1998-6-30 | lld:pubmed |
| pubmed-article:9574450 | pubmed:abstractText | We previously described a method to measure GFR in conscious spontaneously voiding rats. This method circumvents the need for anesthesia and for bladder instrumentation. It's main principle is the correction of renal 125I-iothalamate clearance for incomplete urine collection by the ratio of plasma and renal clearance of co-infused 131I-Hippuran. A disadvantage of this technique is the requirement of an intra-arterial catheter for infusion of the renal function tracers. We therefore tested whether intraperitoneal infusion of 125I-iothalamate and 131I-Hippuran can be used for such a GFR measurement in conscious spontaneously voiding rats. We found that during intraperitoneal administration, stable plasma levels of 131I-Hippuran could be obtained. However, urinary recovery of 131I-Hippuran was incomplete (66 +/- 32%), leading to a significant overestimation of GFR by 140 +/- 13% in comparison with the GFR measured by the intra-arterial technique. Thus intraperitoneal infusion of renal function tracers cannot replace intra-arterial infusion. | lld:pubmed |
| pubmed-article:9574450 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9574450 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9574450 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9574450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9574450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9574450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9574450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9574450 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9574450 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:9574450 | pubmed:issn | 0886-022X | lld:pubmed |
| pubmed-article:9574450 | pubmed:author | pubmed-author:de JongP EPE | lld:pubmed |
| pubmed-article:9574450 | pubmed:author | pubmed-author:de ZeeuwDD | lld:pubmed |
| pubmed-article:9574450 | pubmed:author | pubmed-author:de VriesP APA | lld:pubmed |
| pubmed-article:9574450 | pubmed:author | pubmed-author:NavisGG | lld:pubmed |
| pubmed-article:9574450 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9574450 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:9574450 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9574450 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9574450 | pubmed:pagination | 249-55 | lld:pubmed |
| pubmed-article:9574450 | pubmed:dateRevised | 2008-5-21 | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:meshHeading | pubmed-meshheading:9574450-... | lld:pubmed |
| pubmed-article:9574450 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9574450 | pubmed:articleTitle | Can continuous intraperitoneal infusion of 125I-iothalamate and 131I-hippuran be used for measurement of GFR in conscious rats? | lld:pubmed |
| pubmed-article:9574450 | pubmed:affiliation | Groningen Institute for Drug studies (GIDS), Department of Internal Medicine, University Hospital, The Netherlands. | lld:pubmed |
| pubmed-article:9574450 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9574450 | pubmed:publicationType | Comparative Study | lld:pubmed |
