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pubmed-article:9573399pubmed:abstractTextThe effects of one week of estrogen replacement on choline acetyltransferase (ChAT) and trkA mRNA expression are examined in young and aged rodents to determine whether estrogen continues to affect cholinergic neurons in aging brain. Significant increases in ChAT and trkA are observed in the nucleus basalis of Meynert (nBM) of both age groups. ChAT expression is also increased in the HDB without changes in trkA expression. Results indicate modulation of ChAT expression by estrogen is retained in the aged rodent brain and suggests the possibility that changes in ChAT expression may be dissociated from concurrent alterations in trkA.lld:pubmed
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pubmed-article:9573399pubmed:copyrightInfoCopyright 1998 Elsevier Science B.V.lld:pubmed
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pubmed-article:9573399pubmed:pagination343-6lld:pubmed
pubmed-article:9573399pubmed:dateRevised2009-11-19lld:pubmed
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pubmed-article:9573399pubmed:articleTitleEffects of estrogen replacement on choline acetyltransferase and trkA mRNA expression in the basal forebrain of aged rats.lld:pubmed
pubmed-article:9573399pubmed:affiliationDepartment of Pharmacology, University of Washington, Seattle, WA 98195, USA.lld:pubmed
pubmed-article:9573399pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9573399pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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