| pubmed-article:9555671 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9555671 | lifeskim:mentions | umls-concept:C0016658 | lld:lifeskim |
| pubmed-article:9555671 | lifeskim:mentions | umls-concept:C1709854 | lld:lifeskim |
| pubmed-article:9555671 | lifeskim:mentions | umls-concept:C0450127 | lld:lifeskim |
| pubmed-article:9555671 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
| pubmed-article:9555671 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:9555671 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9555671 | pubmed:dateCreated | 1998-6-11 | lld:pubmed |
| pubmed-article:9555671 | pubmed:abstractText | Fractures occur in 11 to 26% of renal allograft recipients after transplantation despite improvements in bone and mineral disorders. This high fracture rate is likely a consequence of accelerated osteopenia. The cause of posttransplant bone loss is multifactorial, and patients with insulin-dependent diabetes mellitus and renal failure may have additional fracture risks such as low turnover bone disease. This retrospective cohort study was undertaken to determine the long-term incidence and the potential risk factors of posttransplant fractures in patients with insulin-dependent diabetes mellitus undergoing combined kidney-pancreas allograft transplantation. Thirty-five patients with insulin-dependent diabetes mellitus who received a combined kidney-pancreas allograft between 1987 and 1992 were evaluated. Thirty-five kidney allograft recipients matched for age, gender, and the date of transplant were also reviewed. The fracture incidence in the kidney-pancreas group was 49% after transplantation. The rate of first fracture after kidney-pancreas transplantation was 12.1% per patient year, resulting in a 5-yr fracture-free rate of 48%. The initial fracture occurred at a mean of 31.06 +/- 19.9 mo. Steroid exposure was found to increase the risk of fracture, and analysis by means of a Cox regression model estimated that an increase in cumulative steroid exposure of 10 mg/kg at any given month increased the hazard of sustaining a fracture by 9% (95% confidence interval for hazard ratio, 1.01 to 1.18; P = 0.031). This analysis suggests that kidney-pancreas recipients are at significant risk of sustaining a fracture within a few years after transplantation. | lld:pubmed |
| pubmed-article:9555671 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9555671 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9555671 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9555671 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9555671 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9555671 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9555671 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:9555671 | pubmed:issn | 1046-6673 | lld:pubmed |
| pubmed-article:9555671 | pubmed:author | pubmed-author:SpragueS MSM | lld:pubmed |
| pubmed-article:9555671 | pubmed:author | pubmed-author:BruceD SDS | lld:pubmed |
| pubmed-article:9555671 | pubmed:author | pubmed-author:Thistlethwait... | lld:pubmed |
| pubmed-article:9555671 | pubmed:author | pubmed-author:WoodleE SES | lld:pubmed |
| pubmed-article:9555671 | pubmed:author | pubmed-author:JosephsonM... | lld:pubmed |
| pubmed-article:9555671 | pubmed:author | pubmed-author:ChiuM YMY | lld:pubmed |
| pubmed-article:9555671 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9555671 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:9555671 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9555671 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9555671 | pubmed:pagination | 677-83 | lld:pubmed |
| pubmed-article:9555671 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
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| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:meshHeading | pubmed-meshheading:9555671-... | lld:pubmed |
| pubmed-article:9555671 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9555671 | pubmed:articleTitle | Analysis of fracture prevalence in kidney-pancreas allograft recipients. | lld:pubmed |
| pubmed-article:9555671 | pubmed:affiliation | Department of Medicine, University of Chicago, IL 60637, USA. | lld:pubmed |
| pubmed-article:9555671 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9555671 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:9555671 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9555671 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9555671 | lld:pubmed |
