| pubmed-article:9524254 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C0006556 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C1419413 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C1999216 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:9524254 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9524254 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:9524254 | pubmed:dateCreated | 1998-5-13 | lld:pubmed |
| pubmed-article:9524254 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:abstractText | The 2-5A/RNase L system is one of the pathways induced by interferon (IFN). It plays a major role in the antiviral and antiproliferative activities of IFNs. Recently, we have shown that the activity of the RNase L could be inhibited by a proteic inhibitor, the RNase L Inhibitor (RLI). Human RLI (Hu-RLI) was cloned and characterized. We describe here the isolation and characterization of the cDNA encoding the murine RLI (Mu-RLI). Hu-RLI and Mu-RLI protein have 98% amino acid identity. Mu-RLI is functionally homologous to Hu-RLI, and all the structural features and amino acid sequence motifs of Hu-RLI are conserved in Mu-RLI. Moreover, reticulocyte lysate translated Mu-RLI protein is also able to inhibit 2-5A binding on 2-5A-dependent RNAse-L. Northern blot analysis revealed that Mu-RLI cDNA hybridizes with one mRNA of 3.5 kb except for the testis where two mRNA of 3.5 and 2.1 kb, respectively, are detected, suggesting a tissue-specific regulation. | lld:pubmed |
| pubmed-article:9524254 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9524254 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9524254 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9524254 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:9524254 | pubmed:issn | 0378-1119 | lld:pubmed |
| pubmed-article:9524254 | pubmed:author | pubmed-author:LebleuBB | lld:pubmed |
| pubmed-article:9524254 | pubmed:author | pubmed-author:BisbalCC | lld:pubmed |
| pubmed-article:9524254 | pubmed:author | pubmed-author:SalehzadaTT | lld:pubmed |
| pubmed-article:9524254 | pubmed:author | pubmed-author:Benoit De... | lld:pubmed |
| pubmed-article:9524254 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9524254 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:9524254 | pubmed:volume | 209 | lld:pubmed |
| pubmed-article:9524254 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9524254 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9524254 | pubmed:pagination | 149-56 | lld:pubmed |
| pubmed-article:9524254 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:9524254 | pubmed:meshHeading | pubmed-meshheading:9524254-... | lld:pubmed |
| pubmed-article:9524254 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9524254 | pubmed:articleTitle | cDNA cloning and expression analysis of the murine ribonuclease L inhibitor. | lld:pubmed |
| pubmed-article:9524254 | pubmed:affiliation | IGMM-CNRS-UMR 5535, 1919 route de Mende, 34293, Montpellier Cedex 5, France. | lld:pubmed |
| pubmed-article:9524254 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9524254 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:24015 | entrezgene:pubmed | pubmed-article:9524254 | lld:entrezgene |
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