Linked Life Data

9514600

Source:http://linkedlifedata.com/resource/pubmed/id/9514600

Statements in which the resource exists.
SubjectPredicateObjectContext
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pubmed-article:9514600pubmed:dateCreated1998-4-20lld:pubmed
pubmed-article:9514600pubmed:abstractTextFormation of DNA breaking hydroxyfuranone and hydroxypyranone derivatives in the Maillard reaction of glucose and bovine serum albumin (BSA) under physiological conditions was investigated. A mixture of glucose and BSA was incubated at 37 degrees C in water or in 1 M phosphate buffer (pH 7.4). The ethyl acetate/2-propanol extract of the reaction mixtures showed significant DNA breaking activity against supercoiled DNA especially in the presence of Fe(III) ion. Gas chromatography/mass spectrometry analysis of the mixture revealed the formation of DNA breaking hydroxyfuranones (HMF and DMHF) and hydroxypyranone (DDMP).lld:pubmed
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pubmed-article:9514600pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9514600pubmed:year1998lld:pubmed
pubmed-article:9514600pubmed:articleTitleFormation of hydroxyfuranone and hydroxypyranone derivatives with DNA-breaking activity in the Maillard reaction of glucose and albumin under physiological conditions.lld:pubmed
pubmed-article:9514600pubmed:affiliationSchool of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan.lld:pubmed
pubmed-article:9514600pubmed:publicationTypeJournal Articlelld:pubmed