| pubmed-article:9500350 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9500350 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
| pubmed-article:9500350 | lifeskim:mentions | umls-concept:C0017665 | lld:lifeskim |
| pubmed-article:9500350 | pubmed:issue | 9103 | lld:pubmed |
| pubmed-article:9500350 | pubmed:dateCreated | 1998-3-17 | lld:pubmed |
| pubmed-article:9500350 | pubmed:abstractText | Membranous nephropathy is characterised by the deposition of immunoglobulin, predominantly of the IgG4 subclass, along the epithelial surface of the glomerular-basement membrane. Current models of pathogenesis usually assume in-situ immune-complex formation involving an as yet uncharacterised fixed glomerular antigen. I argue that the properties of IgG4 (inability to fix complement and therefore impaired clearance of IgG4-containing complexes; low affinity and therefore ability for IgG4-containing complexes to dissociate and traverse the glomerular-basement membrane) are compatible with a pathogenic mechanism that involves the deposition of circulating IgG4 immune complexes containing diverse antigens. | lld:pubmed |
| pubmed-article:9500350 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9500350 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9500350 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:9500350 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9500350 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9500350 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9500350 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:9500350 | pubmed:issn | 0140-6736 | lld:pubmed |
| pubmed-article:9500350 | pubmed:author | pubmed-author:OliveiraD BDB | lld:pubmed |
| pubmed-article:9500350 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9500350 | pubmed:day | 28 | lld:pubmed |
| pubmed-article:9500350 | pubmed:volume | 351 | lld:pubmed |
| pubmed-article:9500350 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9500350 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9500350 | pubmed:pagination | 670-1 | lld:pubmed |
| pubmed-article:9500350 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:meshHeading | pubmed-meshheading:9500350-... | lld:pubmed |
| pubmed-article:9500350 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9500350 | pubmed:articleTitle | Membranous nephropathy: an IgG4-mediated disease. | lld:pubmed |
| pubmed-article:9500350 | pubmed:affiliation | Division of Renal Medicine, St George's Hospital Medical School, London, UK. | lld:pubmed |
| pubmed-article:9500350 | pubmed:publicationType | Journal Article | lld:pubmed |
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