Linked Life Data

9490638

Source:http://linkedlifedata.com/resource/pubmed/id/9490638

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:9490638rdf:typepubmed:Citationlld:pubmed
pubmed-article:9490638lifeskim:mentionsumls-concept:C0086418lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C0061928lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C0205177lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C1419277lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C1412517lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C1423613lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C1705994lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C1513492lld:lifeskim
pubmed-article:9490638lifeskim:mentionsumls-concept:C1720675lld:lifeskim
pubmed-article:9490638pubmed:dateCreated1998-8-6lld:pubmed
pubmed-article:9490638pubmed:databankReferencehttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:abstractTextThe heavy chains of the class IX myosins, rat myr5 and human myosin-IXb, contain within their tail domains a region with sequence homology to GTPase activating proteins for the rho family of G proteins. Because low levels of myosin-IXb expression preclude purification by conventional means, we have employed an immunoadsorption strategy to purify myosin-IXb, enabling us to characterize the mechanochemical and rho-GTPase activation properties of the native protein. In this report we have examined the light chain content, actin binding properties, in vitro motility and rho-GTPase activity of human myosin-IXb purified from leukocytes. The results presented here indicate that myosin-IXb contains calmodulin as a light chain and that it binds to actin with high affinity in both the absence and presence of ATP. Myosin-IXb is an active motor which, like other calmodulin-containing myosins, exhibits maximal velocity of actin filaments (15 nm/second) in the absence of Ca2+. Native myosin-IXb exhibits GAP activity on rho. Class IX myosins may be an important link between rho and rho-dependent remodeling of the actin cytoskeleton.lld:pubmed
pubmed-article:9490638pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:languageenglld:pubmed
pubmed-article:9490638pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:citationSubsetIMlld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9490638pubmed:statusMEDLINElld:pubmed
pubmed-article:9490638pubmed:monthAprlld:pubmed
pubmed-article:9490638pubmed:issn0021-9533lld:pubmed
pubmed-article:9490638pubmed:authorpubmed-author:MoosekerM SMSlld:pubmed
pubmed-article:9490638pubmed:authorpubmed-author:BokochG MGMlld:pubmed
pubmed-article:9490638pubmed:authorpubmed-author:PostP LPLlld:pubmed
pubmed-article:9490638pubmed:issnTypePrintlld:pubmed
pubmed-article:9490638pubmed:volume111 ( Pt 7)lld:pubmed
pubmed-article:9490638pubmed:ownerNLMlld:pubmed
pubmed-article:9490638pubmed:authorsCompleteYlld:pubmed
pubmed-article:9490638pubmed:pagination941-50lld:pubmed
pubmed-article:9490638pubmed:dateRevised2009-11-19lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:meshHeadingpubmed-meshheading:9490638-...lld:pubmed
pubmed-article:9490638pubmed:year1998lld:pubmed
pubmed-article:9490638pubmed:articleTitleHuman myosin-IXb is a mechanochemically active motor and a GAP for rho.lld:pubmed
pubmed-article:9490638pubmed:affiliationDepartment of Molecular Biology, Yale University, New Haven, CT 06520, USA. penny.post@yale.edulld:pubmed
pubmed-article:9490638pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9490638pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:9490638pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:58entrezgene:pubmedpubmed-article:9490638lld:entrezgene
entrez-gene:801entrezgene:pubmedpubmed-article:9490638lld:entrezgene
entrez-gene:4650entrezgene:pubmedpubmed-article:9490638lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:9490638lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:9490638lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9490638lld:pubmed