pubmed-article:9477328 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0029246 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0007776 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0022655 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0001613 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0010834 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0242608 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0025979 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0949989 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
pubmed-article:9477328 | lifeskim:mentions | umls-concept:C1511572 | lld:lifeskim |
pubmed-article:9477328 | pubmed:issue | 7 | lld:pubmed |
pubmed-article:9477328 | pubmed:dateCreated | 1998-5-4 | lld:pubmed |
pubmed-article:9477328 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:abstractText | nuclear fallout (nuf) is a maternal effect mutation that specifically disrupts the cortical syncytial divisions during Drosophila embryogenesis. We show that the nuf gene encodes a highly phosphorylated novel protein of 502 amino acids with C-terminal regions predicted to form coiled-coils. During prophase of the late syncytial divisions, Nuf concentrates at the centrosomes and is generally cytoplasmic throughout the rest of the nuclear cycle. In nuf-derived embryos, the recruitment of actin from caps to furrows during prophase is disrupted. This results in incomplete metaphase furrows specifically in regions distant from the centrosomes. The nuf mutation does not disrupt anillin or peanut recruitment to the metaphase furrows indicating that Nuf is not involved in the signaling of metaphase furrow formation. These results also suggest that anillin and peanut localization are independent of actin localization to the metaphase furrows. nuf also disrupts the initial stages of cellularization and produces disruptions in cellularization furrows similar to those observed in the metaphase furrows. The localization of Nuf to centrosomal regions throughout cellularization suggests that it plays a similar role in the initial formation of both metaphase and cellularization furrows. A model is presented in which Nuf provides a functional link between centrosomes and microfilaments. | lld:pubmed |
pubmed-article:9477328 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:language | eng | lld:pubmed |
pubmed-article:9477328 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9477328 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9477328 | pubmed:month | Apr | lld:pubmed |
pubmed-article:9477328 | pubmed:issn | 0950-1991 | lld:pubmed |
pubmed-article:9477328 | pubmed:author | pubmed-author:FogartyPP | lld:pubmed |
pubmed-article:9477328 | pubmed:author | pubmed-author:SullivanWW | lld:pubmed |
pubmed-article:9477328 | pubmed:author | pubmed-author:FieldC MCM | lld:pubmed |
pubmed-article:9477328 | pubmed:author | pubmed-author:RothwellW FWF | lld:pubmed |
pubmed-article:9477328 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9477328 | pubmed:volume | 125 | lld:pubmed |
pubmed-article:9477328 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9477328 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9477328 | pubmed:pagination | 1295-303 | lld:pubmed |
pubmed-article:9477328 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:meshHeading | pubmed-meshheading:9477328-... | lld:pubmed |
pubmed-article:9477328 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9477328 | pubmed:articleTitle | Nuclear-fallout, a Drosophila protein that cycles from the cytoplasm to the centrosomes, regulates cortical microfilament organization. | lld:pubmed |
pubmed-article:9477328 | pubmed:affiliation | Department of Biology, University of California, Santa Cruz, California 95064, USA. | lld:pubmed |
pubmed-article:9477328 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9477328 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:9477328 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:35696 | entrezgene:pubmed | pubmed-article:9477328 | lld:entrezgene |
entrez-gene:35801 | entrezgene:pubmed | pubmed-article:9477328 | lld:entrezgene |
entrez-gene:39572 | entrezgene:pubmed | pubmed-article:9477328 | lld:entrezgene |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9477328 | lld:pubmed |