| pubmed-article:9465062 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0003392 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0028426 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0376196 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0237477 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C1621812 | lld:lifeskim |
| pubmed-article:9465062 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:9465062 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9465062 | pubmed:dateCreated | 1998-3-19 | lld:pubmed |
| pubmed-article:9465062 | pubmed:abstractText | An alkaloid from opium, noscapine, is used as an antitussive drug and has low toxicity in humans and mice. We show that noscapine binds stoichiometrically to tubulin, alters its conformation, affects microtubule assembly, and arrests mammalian cells in mitosis. Furthermore, noscapine causes apoptosis in many cell types and has potent antitumor activity against solid murine lymphoid tumors (even when the drug was administered orally) and against human breast and bladder tumors implanted in nude mice. Because noscapine is water-soluble and absorbed after oral administration, its chemotherapeutic potential in human cancer merits thorough evaluation. | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9465062 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9465062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9465062 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9465062 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:9465062 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:KappJ AJA | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:ShanksJJ | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:JoshiH CHC | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:PetrovGG | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:JuHH | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:YeKK | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:TekmalR RRR | lld:pubmed |
| pubmed-article:9465062 | pubmed:author | pubmed-author:KeshavaNN | lld:pubmed |
| pubmed-article:9465062 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9465062 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:9465062 | pubmed:volume | 95 | lld:pubmed |
| pubmed-article:9465062 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9465062 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9465062 | pubmed:pagination | 1601-6 | lld:pubmed |
| pubmed-article:9465062 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:meshHeading | pubmed-meshheading:9465062-... | lld:pubmed |
| pubmed-article:9465062 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9465062 | pubmed:articleTitle | Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells. | lld:pubmed |
| pubmed-article:9465062 | pubmed:affiliation | Graduate Program in Biochemistry and Molecular Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. | lld:pubmed |
| pubmed-article:9465062 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9465062 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9465062 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9465062 | lld:pubmed |
