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pubmed-article:9461663pubmed:abstractTextThe principal active anxiolytic components in Saiboku-to, an Oriental herbal medicine, have been isolated and identified as magnolol (5,5'-di-2-propenyl-1,1'-biphenyl-2,2'-diol) and honokiol (3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol). Evaluation by means of an elevated plus-maze test showed that honokiol was at least 5000 times more potent than Saiboku-to when mice were treated orally for 7 days.lld:pubmed
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pubmed-article:9461663pubmed:articleTitleIdentification of magnolol and honokiol as anxiolytic agents in extracts of saiboku-to, an oriental herbal medicine.lld:pubmed
pubmed-article:9461663pubmed:affiliationDepartment of Neuropsychopharmacology, Gunma University School of Medicine, Japan. yuji@news.sb.gunma-u.ac.jplld:pubmed
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