| pubmed-article:9437831 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9437831 | lifeskim:mentions | umls-concept:C0042803 | lld:lifeskim |
| pubmed-article:9437831 | lifeskim:mentions | umls-concept:C0024109 | lld:lifeskim |
| pubmed-article:9437831 | lifeskim:mentions | umls-concept:C0036945 | lld:lifeskim |
| pubmed-article:9437831 | lifeskim:mentions | umls-concept:C0085236 | lld:lifeskim |
| pubmed-article:9437831 | lifeskim:mentions | umls-concept:C1819461 | lld:lifeskim |
| pubmed-article:9437831 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:9437831 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:9437831 | pubmed:dateCreated | 1998-2-12 | lld:pubmed |
| pubmed-article:9437831 | pubmed:abstractText | Sheep naturally infected by visna-maedi virus often develop a chronic interstitial lung disease characterized by an alveolitis comprising lymphocytes, neutrophils and macrophages. The alpha chemokine interleukin-8 (IL-8) was detected in cell free bronchoalveolar lavage fluid from naturally infected animals, confirmed by RT-PCR, presenting typical lesions of maedi and elevated total alveolar cell counts. No detectable IL-8 was found in the fluid obtained from uninfected animals. IL-8 concentration in alveolar fluid is correlated with alveolar neutrophil counts. Bronchoalveolar lavage cells from infected animals were found to contain a large amount of IL-8 mRNA and may contribute to IL-8 production. In situ hybridization showed that macrophages were the predominant cell type expressing IL-8 mRNA. Sustained production of IL-8 by alveolar macrophages during visna-maedi infection could suffice for neutrophil attraction to the alveoli, and may contribute to the development of lesions. | lld:pubmed |
| pubmed-article:9437831 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9437831 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9437831 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9437831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9437831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9437831 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9437831 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9437831 | pubmed:issn | 0165-2427 | lld:pubmed |
| pubmed-article:9437831 | pubmed:author | pubmed-author:MornexJ FJF | lld:pubmed |
| pubmed-article:9437831 | pubmed:author | pubmed-author:CordierGG | lld:pubmed |
| pubmed-article:9437831 | pubmed:author | pubmed-author:CottinVV | lld:pubmed |
| pubmed-article:9437831 | pubmed:author | pubmed-author:LegasteloisII | lld:pubmed |
| pubmed-article:9437831 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9437831 | pubmed:day | 6 | lld:pubmed |
| pubmed-article:9437831 | pubmed:volume | 59 | lld:pubmed |
| pubmed-article:9437831 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9437831 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9437831 | pubmed:pagination | 131-9 | lld:pubmed |
| pubmed-article:9437831 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:meshHeading | pubmed-meshheading:9437831-... | lld:pubmed |
| pubmed-article:9437831 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9437831 | pubmed:articleTitle | Alveolar macrophages from sheep naturally infected by visna-maedi virus contribute to IL-8 production in the lung. | lld:pubmed |
| pubmed-article:9437831 | pubmed:affiliation | Laboratoire d'Immunologie et de Biologie Pulmonaire, Université Claude Bernard, Hôpital Louis Pradel, Lyon, France. | lld:pubmed |
| pubmed-article:9437831 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9437831 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9437831 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9437831 | lld:pubmed |
