| pubmed-article:9436269 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C1334146 | lld:lifeskim |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C0272187 | lld:lifeskim |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9436269 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9436269 | pubmed:issue | 3-4 | lld:pubmed |
| pubmed-article:9436269 | pubmed:dateCreated | 1998-2-19 | lld:pubmed |
| pubmed-article:9436269 | pubmed:abstractText | Peripheral blood leukocytes of 11 normal cows, 7 cows heterozygous and 2 heifers homozygous for bovine leukocyte adhesion deficiency (BLAD) were analysed by flow cytometry for the intensity of their beta 2 integrin expression (LFA-1(CD11a/CD18), CR3 (CD11b/CD18) and CR4 (CD11c/CD18)). BLAD-homozygotes revealed no or a very weak expression of the beta 2 integrins and had a 10-fold and 4- to 5-fold increase in absolute number of neutrophils and monocytes, respectively, whereas the absolute number of lymphocytes remained normal. The mean fluorescence intensity (MFI) of the beta 2 integrins (CD18) in heterozygous animals was 56 to 90% of this in the normal cows (MFI between 14 and 512). The difference in the expression level was most pronounced for LFA-1 on the small cluster of lymphocytes with the highest MFI for LFA-1. Repeated analysis and phorbol myristate acetate stimulation revealed that the LFA-1 expression on this high-expressing cell population of the peripheral blood allowed a ready identification of BLAD-heterozygotes by flow cytometry. | lld:pubmed |
| pubmed-article:9436269 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9436269 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9436269 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9436269 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9436269 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9436269 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9436269 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9436269 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:9436269 | pubmed:issn | 0165-2427 | lld:pubmed |
| pubmed-article:9436269 | pubmed:author | pubmed-author:CoxEE | lld:pubmed |
| pubmed-article:9436269 | pubmed:author | pubmed-author:MastJJ | lld:pubmed |
| pubmed-article:9436269 | pubmed:author | pubmed-author:GoddeerisB... | lld:pubmed |
| pubmed-article:9436269 | pubmed:author | pubmed-author:SchwengerBB | lld:pubmed |
| pubmed-article:9436269 | pubmed:author | pubmed-author:MacHughNN | lld:pubmed |
| pubmed-article:9436269 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9436269 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:9436269 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:9436269 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9436269 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9436269 | pubmed:pagination | 249-63 | lld:pubmed |
| pubmed-article:9436269 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:meshHeading | pubmed-meshheading:9436269-... | lld:pubmed |
| pubmed-article:9436269 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9436269 | pubmed:articleTitle | Expression of beta 2 integrins on blood leukocytes of cows with or without bovine leukocyte adhesion deficiency. | lld:pubmed |
| pubmed-article:9436269 | pubmed:affiliation | Laboratory of Veterinary Immunology, Faculty of Veterinary Medicine, Universiteit Gent, Merelbeke, Belgium. eric.cox@rug.ac.be | lld:pubmed |
| pubmed-article:9436269 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9436269 | lld:pubmed |
