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pubmed-article:9396067pubmed:abstractTextPlasma ET-1 was measured around the clock on different calendar dates in healthy subjects and in subjects with diabetes and/or with high blood pressure and/or a history of vascular complications (HVDR). A transverse approach, with each subject contributing a single 24-h mean, assessed any about-weekly or half-weekly variation in ET-1. A circasemiseptan component resolved by single cosinor for nondiabetic (but not for diabetic) HVDR subjects (p = 0.010) differs in its timing of overall high values (p < 0.050) from that found in healthy subjects (p = 0.006). The results are aligned with circasemiseptan patterns in other circulatory variables and morbidity/mortality statistics.lld:pubmed
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pubmed-article:9396067pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9396067pubmed:articleTitleAbout-half-weekly (circasemiseptan) component of the endothelin-1 (ET-1) chronome and vascular disease risk.lld:pubmed
pubmed-article:9396067pubmed:affiliationUniversity of Minnesota, Department of Laboratory Medicine and Pathology, Lyon Laboratories, Minneapolis 55455, USA.lld:pubmed
pubmed-article:9396067pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9396067pubmed:publicationTypeComparative Studylld:pubmed